Oxalate is a metabolic end product excreted by the kidney.Mild increases in urinary oxalate are most commonly associated with Nephrolithiasis.Chronically high levels of urinary oxalate, as seen in patients with primary hyperoxaluria, are driving factor for recurrent renal stones, and ultimately lead to renal failure, calcification of soft tissue an
PI3K/AKT/mTOR-Targeted Therapy for Breast Cancer
Phosphatidylinositol 3-kinase (PI3K), protein kinase B (PKB/AKT) and mechanistic target of rapamycin (mTOR) (PAM) pathways play important roles in breast bostik mvp tumorigenesis and confer worse prognosis in breast cancer patients.The inhibitors targeting three key nodes of these pathways, PI3K, AKT and mTOR, are continuously developed.For breast
A Novel Binary QUasi-Affine TRansformation Evolutionary (QUATRE) Algorithm
QUasi-Affine TRansformation Evolutionary (QUATRE) algorithm generalized differential evolution (DE) algorithm to matrix form.QUATRE was originally designed for a continuous search space, but many practical applications are rawafricaonline.com binary optimization problems.Therefore, we designed a novel binary version of QUATRE.The proposed binary al
On the Development of a Protection Profile Module for Encryption Key Management Components
The ability of a cryptographic system to protect information from attacks depends on many factors, including the secrecy of the encryption key.A crucial aspect of any cryptosystem is how it manages the encryption keys.Encryption Key Management (EKM) spans the entire life cycle of the key, including the key’s generation, usage, distribution,
APPLICATION OF ELECTRONIC TACHEOMETER FOR PREAND POST-CONSTRUCTION SURVEY OF ELEVATOR SHAFT
Floor-by-floor survey of installed elements of an elevator shaft using coordinate method and tacheometer is also inhibited by the necessity to determine device installation points for floors of every mounting horizon that leads to additional measurements due to conditions of the completed building framework and presence of a great number of situati